This is Yuval Noah Harari's third book (and our third Note). His first two focused on the past (Sapiens) and the future (Homo Deus). In this one, we "zoom in on the here and now" as we take a look at 21 of the most important things to be thinking about in the 21st century. Like all of his books, this is a thoughtful and thought-provoking look at some globally Big Ideas. Although obviously outside the scope of our normal Optimizing, I think it's important stuff. In the Note we explore dealing with "Disillusionment" (the title of chapter #1) by switching from "panic to bewilderment"), the future of health care and driving (and jobs!), making sure we match our investment in developing AI with an equivalent investment in developing "human consciousness," what we should be teaching our kids (basically, how to Optimize!!), and Yuval's #1 practice: meditation.